Optimal One-Arm Two-Stage Phase II Design with Survival Endpoint


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Documentation for package ‘OneArm2stage’ version 1.1.5

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FitDat Fit Historical Survival Data Assuming the Failure Time Follows the Weibull Distribution
LRT Conduct Interim or Final Analyses Using One-Sample Log-Rank Test for the Optimal Two-Stage Trials
Optimal.KJ Optimal Two-Stage Design Using One-Sample Log-Rank Test with Unrestricted Follow-Up
Optimal.rKJ Optimal Two-Stage Design Using One-Sample Log-Rank Test with Restricted Follow-Up
Sim_KJ Calculate Empirical Power by Simulation for the Optimal Two-Stage Design Using One-Sample Log-Rank Test with Unrestricted Follow-Up
Sim_rKJ Calculate Empirical Power by Simulation for the Optimal Two-Stage Design Using One-Sample Log-Rank Test with Restricted Follow-Up