Seamless 'Nonmem' Simulation Platform

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Documentation for package ‘NMsim’ version 0.2.4

• DESCRIPTION file.
• Package NEWS.

Help Pages

add	Create function that adds text elements to vector
addEVID2	Add simulation records to dosing records
addResVar	Add residual variability based on parameter estimates
as.NMctl	Convert object to class NMctl
cbind.NMsimModTab	Remove NMsimModTab class and discard NMsimModTab meta data
cbind.NMsimRes	Remove NMsimRes class and discard NMsimRes meta data
dimnames.NMsimModTab	Remove NMsimModTab class and discard NMsimModTab meta data
dimnames.NMsimRes	Remove NMsimRes class and discard NMsimRes meta data
expandCovs	Create data set where each covariate is univariately varied (see 'forestDefineCovs()')
forestDefineCovs	Create data set where each covariate is univariately varied
forestSummarize	Summarize simulated exposures relative to reference subject
genPhiFile	Generate a .phi file for further simulation with Nonmem
inputArchiveDefault	Default location of input archive file
is.NMsimModTab	Remove NMsimModTab class and discard NMsimModTab meta data
is.NMsimRes	Remove NMsimRes class and discard NMsimRes meta data
merge.NMsimModTab	Remove NMsimModTab class and discard NMsimModTab meta data
merge.NMsimRes	Remove NMsimRes class and discard NMsimRes meta data
modTab	Get NMsim model metadata
NMaddSamples	Add simulation (sample) records to dosing records
NMcreateDoses	Easily and flexibly generate dosing records
NMexec	Execute Nonmem and archive input data with model files
NMreadSim	Read simulation results based on NMsim's track of model runs
NMsim	Simulate from an estimated Nonmem model
NMsimModTabOperations	Remove NMsimModTab class and discard NMsimModTab meta data
NMsimResOperations	Remove NMsimRes class and discard NMsimRes meta data
NMsimTestConf	Summarize and test NMsim configuration
NMsim_asis	Simulation method that uses the provided control stream as is
NMsim_default	Transform an estimated Nonmem model into a simulation control stream
NMsim_EBE	Use emperical Bayes estimates to simulate re-using ETAs
NMsim_NWPRI	Simulate with parameter variability using the NONMEM NWPRI subroutine
NMsim_typical	Typical subject simiulation method
NMsim_VarCov	Simulate with parameter values sampled from a covariance step
NMwriteInits	Writes a parameter values to a control stream
NMwriteSizes	Create or update $SIZES in a control stream
overwrite	Create function that modifies text elements in a vector Namely used to feed functions to modify control streams using 'NMsim()' arguments such as 'modify'. Those functions are often onveniently passed a function. 'add' and 'overwrite' are simple shortcuts to creating such functions. Make sure to see examples.
print.summary_NMsimRes	print method for NMsimRes summaries
rbind.NMsimModTab	Remove NMsimModTab class and discard NMsimModTab meta data
rbind.NMsimRes	Remove NMsimRes class and discard NMsimRes meta data
readCtl	Read as class NMctl
readParsWide	Parameter data from csv
sampleCovs	Sample subject-level covariates from an existing data set
samplePars	Sample model parameters using 'mvrnorm' or the 'simpar' package
sampleParsSimpar	Sample model parameters using the 'simpar' package
simPopEtas	Generate a population based on a Nonmem model
summarizeCovs	Summarize simulated exposures relative to reference subject (see 'forestSummarize()')
summary.NMsimRes	summary method for NMsim results (NMsimRes objects)
t.NMsimModTab	Remove NMsimModTab class and discard NMsimModTab meta data
t.NMsimRes	Remove NMsimRes class and discard NMsimRes meta data
unNMsimModTab	Remove NMsimModTab class and discard NMsimModTab meta data
unNMsimRes	Remove NMsimRes class and discard NMsimRes meta data